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Search Results for " sp ii "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T38260	SP 600125, negative control	JNK Inhibitor II, negative control
	SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β/MKK7 (growth arrest and DNA damage-inducible β/me...
T3109	SP600125	1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone	Apoptosis , Ferroptosis , Trk receptor , JNK , Aurora Kinase , Autophagy
	SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
T21697	Sp-Cyclic AMPS (sodium salt)
	Sp-cAMPS sodium salt is an analog of cAMP that is a potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS sodium salt is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a K i of 47.6 μM. Sp-cA...
T38302	Chrysomycin B
	Chrysomycin B is an antibiotic isolated from Streptomyces sp. Chrysomycin B induces DNA damage and inhibits topoisomerase II in the human lung adenocarcinoma A549 cell line.
T73708	Sp-cAMPS triethylamine
	Sp-cAMPS triethylamine, a cAMP analog, serves as a potent activator of cAMP-dependent PKA I and II and acts as a competitive inhibitor of phosphodiesterase (PDE3A) with a K i of 47.6 µM. Additionally, it binds the PDE10 ...
T38694	Sp-8-CPT-cAMPS
	Sp-8-CPT-cAMPS is a powerful and specific cAMP analog that activates cAMP-dependent protein kinase A (PKA I and PKA II) selectively and effectively. It exhibits a 153-fold preference for site A of RI over site A of RII, ...

Compounds

SP 600125, negative control

T38260

Synonym: JNK Inhibitor II, negative control

Target:

SP600125

T3109

Synonym: 1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone

Target: Apoptosis, Ferroptosis, Trk receptor, JNK, Aurora Kinase, Autophagy

Sp-Cyclic AMPS (sodium salt)

Sp-cAMPS triethylamine

Cat No.	Product Name	Synonyms	Targets
T15636	K-252a	Antibiotic K 252a,Antibiotic SF 2370,SF2370	Others
	K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphoryla...		Others
T28379	PF-1163B	PF1163B,(-)-PF1163B,PF 1163B
	PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candid...

Natural Products

K-252a

T15636

Synonym: Antibiotic K 252a,Antibiotic SF 2370,SF2370

Target: Others

PF-1163B

T28379

Synonym: PF1163B,(-)-PF1163B,PF 1163B

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01028	BSPII Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucl...
TMPK-00848	BSPII Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BSPII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.3 kDa and the accession number is P21815.
TMPK-00498	BSPII Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	BSPII Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.63 kDa and the accession number is A0A2K5UM27.
TMPJ-00445	IBSP Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize...
TMPY-06810	SFTPB Protein, Human, Recombinant (His)	Human	CHO Cells
	Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by noncil...